Group members
- Prof. Helen Cooper
- Dr Jinglei Yu
- Dr Todd Mize
- Dr Oliver Hale
- Edwin Aponte Angarita
- Peter Macey
- Yuying Du
Former group members
- Dr Emma Sisley
- Dr James Hughes
- Dr Jana Havlikova
- Rebecca Davis
- Dr Eva Illes-Toth
- Dr Anna Simmonds
- Dr Rian Griffiths
- Dr Klaudia Kocurek
- Dr Tom Powell
- Gloria Ulasi
- Dr Andrea Lopez-Clavijo
- Dr Andrew Creese
- Dr Alex Dexter
- Dr Rebecca Edwards
- Dr Andrew Jones
- Dr Malgorzata Kaczorowska
- Dr Nick Martin
- Dr Victor Mikhailov
- Dr Elizabeth Randall
- Dr Joscelyn Sarsby
- Dr Steve Sweet
- Dr Cleidiane Zampronio
- Dr Hongyan Zhao
Dr James Hughes
I am a post-doctoral research fellow working within the NAMS project to develop mass spectrometry as a tool for the analysis of intact protein complexes directly from biological tissue. I previously studied for my PhD under the supervision of Professor Helen Cooper where my work focussed on the development of mass spectrometry methods for the diagnosis and stratification of non-alcoholic fatty liver disease.
Publications
https://orcid.org/0000-0001-6229-7880
2022
- E. Illes-Toth, O. J. Hale, J. W. Hughes, N. Strittmatter, J. Rose, B. Clayton, R. Sargeant, S. Jones, A. Dannhorn, R. J. Goodwin, H.J. Cooper. Mass Spectrometry Detection and Imaging of a Non-Covalent Protein–Drug Complex in Tissue from Orally Dosed Rats. Angew. Chem. Int. Ed. 2022.
- O.J. Hale, J. W. Hughes, E.K. Sisley, H.J. Cooper. Native Ambient Mass Spectrometry Enables Analysis of Intact Endogenous Protein Assemblies up to 145 kDa Directly from Tissue. Anal. Chem. 2022, 94, 14, 5608–5614.
- O.J. Hale, J. W. Hughes and H.J. Cooper. Simultaneous spatial, conformational, and mass analysis of intact proteins and protein assemblies by nano-DESI travelling wave ion mobility mass spectrometry imaging, International Journal of Mass Spectrometry, 2021, 468, 116656.
- R.L. Griffiths, J. Hughes, S.E. Abbatiello, M.W. Belford, I.B. Styles and H.J. Cooper. Comprehensive LESA Mass Spectrometry Imaging of Intact Proteins by Integration of Cylindrical FAIMS. Analytical Chemistry, 2885-2890.
- D. Lighter, J. Hughes, I.B. Styles, A. Filer and H. Dehghani. Multispectral, non-contact diffuse optical tomography of healthy human finger joints. Biomedical Optics Express, 1445-1460.
