Sherzod Nazarov

Sherzod Nazazrov , mass spectrometry PhD student -->

I joined the Cooper group as a PhD student in January 2025, my project focuses on the development of native ambient mass spectrometry (NAMS) methods for in situ analysis of proteins in tissue. NAMS is an emerging field that enables label-free characterization of proteins and their complexes directly from their physiological environment. My research aims to elucidate the underlying mechanisms of extracting native proteins and to identify the optimal sampling and analysis conditions. To achieve this, I will develop techniques for applying NAMS to various types of tissues, with particular attention on its applications in drug discovery. This project has the potential to significantly advance life sciences research by providing critical insights into protein dynamics in their native contexts. With a background in the pharmaceutical field, having completed my MSc at De Montfort University in 2022, I am eager to explore how NAMS can bridge the gap between analytical chemistry and biological research